منابع مشابه
Remarks on E1-E2 and E1-M1 two-photon transitions
2014 We investigate the possibility to observe Doppler-free two-photon transitions in the case where one of the transitions is an electric dipole transition and the other one is a magnetic dipole or an electric quadrupole transition. We show that it is not possible to obtain Doppler-free lines by reflecting the beam on itself. On the other hand, such an effect should be observable if the two co...
متن کاملThe E1 Proteins
The papillomavirus E1 protein is the ‘initiator’ protein for viral DNA replication and thus plays a critical role in maintenance of the viral genome as an episome during the viral life cycle. E1 shows some sequence and structural similarities to the simian virus 40 and polyomavirus large T antigen initiators (12), and its biochemical properties are consistent with its role as a replication init...
متن کاملArchitectural Design of E1
Modern distributed operating systems provide users with transparent access to all resources of the computer network by means of distributed object abstraction. The access reliability and efficiency of such systems are determined by the internal implementation of the given abstraction. The existing architectures are based either on the centralized storage of the object state in one of network no...
متن کاملThe E1 proteins.
E1, an ATP-dependent DNA helicase, is the only enzyme encoded by papillomaviruses (PVs). It is essential for replication and amplification of the viral episome in the nucleus of infected cells. To do so, E1 assembles into a double-hexamer at the viral origin, unwinds DNA at the origin and ahead of the replication fork and interacts with cellular DNA replication factors. Biochemical and structur...
متن کاملImpact of E1 and Cre on Adenovirus Vector Amplification: Developing MDCK CAV-2-E1 and E1-Cre Transcomplementing Cell Lines
Adenovirus vectors have been extensively studied through the manipulation of viral genome. However, little attention is being paid to their producer cell-lines; cells are selected according to virus yields, neglecting the expression profile of transcomplementing gene products underlying cell performance. This work evaluates the impact of E1 (E1A and E1B) and Cre recombinase levels in the produc...
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ژورنال
عنوان ژورنال: Nature Reviews Molecular Cell Biology
سال: 2008
ISSN: 1471-0072,1471-0080
DOI: 10.1038/nrm2478